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Gene: LILRB2 (leukocyte immunoglobulin like receptor B2) Homo sapiens
Symbol: LILRB2
Name: leukocyte immunoglobulin like receptor B2
CRRD ID: 1353018
Description: Exhibits several functions, including MHC protein binding activity; amyloid-beta binding activity; and protein homodimerization activity. Involved in several processes, including Fc receptor mediated inhibitory signaling pathway; cellular response to lipopolysaccharide; and regulation of T cell activation. Localizes to cell surface; cytoplasm; and extracellular space.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD85 antigen-like family member D; CD85D; eukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6; Ig-like transcript 4; ILT-4; ILT4; immunoglobulin-like transcript 4; leucocyte Ig-like receptor B2; leukocyte immunoglobulin-like receptor 2; leukocyte immunoglobulin-like receptor subfamily B member 2; leukocyte immunoglobulin-like receptor subfamily B member 2 soluble isoform; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2; LILRA6; LIR-2; LIR2; MIR-10; MIR10; monocyte/macrophage immunoglobulin-like receptor 10; myeloid inhibitory receptor 10
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1954,273,821 - 54,281,184 (-)EnsemblGRCh38hg38GRCh38
GRCh381954,273,812 - 54,281,110 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371954,777,675 - 54,785,033 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361959,469,487 - 59,476,818 (-)NCBINCBI36hg18NCBI36
Build 341959,470,131 - 59,476,762NCBI
Cytogenetic Map19q13.42NCBI
HuRef1951,105,316 - 51,112,671 (-)NCBIHuRef
CHM1_11954,778,840 - 54,786,197 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on LILRB2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1353018
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.