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Gene: GPR143 (G protein-coupled receptor 143) Homo sapiens
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Symbol: GPR143
Name: G protein-coupled receptor 143
Description: This gene encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in this gene cause ocular albinism type 1, also referred to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y. [provided by RefSeq, Dec 2009]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: G-protein coupled receptor 143; NYS6; OA1; ocular albinism 1; ocular albinism type 1 protein
Orthologs:
Mus musculus (house mouse) : Gpr143 (G protein-coupled receptor 143)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gpr143 (G protein-coupled receptor 143)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gpr143 (G protein-coupled receptor 143)
Pan paniscus (bonobo/pygmy chimpanzee) : GPR143 (G protein-coupled receptor 143)
Canis lupus familiaris (dog) : GPR143 (G protein-coupled receptor 143)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gpr143 (G protein-coupled receptor 143)
Sus scrofa (pig) : GPR143 (G protein-coupled receptor 143)
more info ...
Related Pseudogenes: GPR143P  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X9,725,413 - 9,786,260 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X9,693,453 - 9,734,005 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X9,653,454 - 9,693,917 (-)NCBINCBI36hg18NCBI36
Build 34X9,503,189 - 9,543,653NCBI
CeleraX13,865,374 - 13,905,925 (-)NCBI
Cytogenetic MapXp22.2NCBI
HuRefX7,525,733 - 7,566,160 (-)NCBIHuRef
CHM1_1X9,723,929 - 9,764,313 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on GPR143
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1353035
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.