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Gene: MAGEB3 (MAGE family member B3) Homo sapiens
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Symbol: MAGEB3
Name: MAGE family member B3
Description: This gene is a MAGE-B subfamily member of the MAGE gene family. MAGE family member proteins direct the expression of tumor antigens recognized on a human melanoma by autologous cytolytic T lymphocytes. There are two known clusters of MAGE genes on chromosome X. The members of the MAGE-A subfamily are located in the Xq28 region, while the members of the MAGE-B subfamily are clustered in the Xp21 region. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cancer/testis antigen family 3, member 5; CT3.5; MAGE-B3 antigen; melanoma antigen family B, 3; melanoma antigen family B3; melanoma-associated antigen B3
Orthologs:
Mus musculus (house mouse) : Gm44 (predicted gene 44)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mageb3 (MAGE family member B3)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : MAGEB3 (MAGE family member B3)
Canis lupus familiaris (dog) : MAGEB3 (MAGE family member B3)
Sus scrofa (pig) : MAGEB3 (MAGE family member B3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X30,230,436 - 30,237,493 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X30,248,553 - 30,255,612 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X30,158,474 - 30,165,528 (+)NCBINCBI36hg18NCBI36
Build 34X30,008,209 - 30,015,264NCBI
CeleraX34,370,173 - 34,377,229 (+)NCBI
Cytogenetic MapXp21.2NCBI
HuRefX27,985,506 - 27,992,557 (+)NCBIHuRef
CHM1_1X30,279,495 - 30,286,489 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on MAGEB3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1353042
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.