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Gene: AURKA (aurora kinase A) Homo sapiens
Symbol: AURKA
Name: aurora kinase A
Description: Exhibits protein heterodimerization activity; protein kinase binding activity; and protein serine/threonine kinase activity. Involved in several processes, including liver regeneration; peptidyl-serine phosphorylation; and regulation of protein stability. Localizes to several cellular components, including the nucleoplasm; perinuclear region of cytoplasm; and spindle pole. Colocalizes with the spindle microtubule. Implicated in ovarian cancer and uterine cancer. Biomarker of carcinoma (multiple); invasive ductal carcinoma; prostate carcinoma in situ; and urinary bladder cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AIK; ARK-1; ARK1; AURA; aurora 2; Aurora-A kinase; aurora-related kinase 1; aurora/IPL1-like kinase; aurora/IPL1-related kinase 1; AURORA2; breast tumor-amplified kinase; breast-tumor-amplified kinase; BTAK; hARK1; IPL1-related kinase; MGC34538; PPP1R47; protein phosphatase 1, regulatory subunit 47; serine/threonine kinase 6; serine/threonine protein kinase 15; serine/threonine-protein kinase 15; serine/threonine-protein kinase 6; serine/threonine-protein kinase aurora-A; STK15; STK6; STK7
Mus musculus (house mouse) : Aurka (aurora kinase A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Aurka (aurora kinase A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aurka (aurora kinase A)
Pan paniscus (bonobo/pygmy chimpanzee) : AURKA (aurora kinase A)
Canis lupus familiaris (dog) : AURKA (aurora kinase A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aurka (aurora kinase A)
Sus scrofa (pig) : AURKA (aurora kinase A)
more info ...
Related Pseudogenes: AURKAP1   AURKAP2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh382056,369,389 - 56,392,337 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372054,944,445 - 54,967,351 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362054,377,852 - 54,400,758 (-)NCBINCBI36hg18NCBI36
Celera2051,683,792 - 51,707,784 (-)NCBI
Cytogenetic Map20q13.2NCBI
HuRef2051,729,262 - 51,752,229 (-)NCBIHuRef
CHM1_12054,845,539 - 54,868,486 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on AURKA
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1353168
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.