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Gene: BEX2 (brain expressed X-linked 2) Homo sapiens
Symbol: BEX2
Name: brain expressed X-linked 2
Description: This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BEX1; brain-expressed X-linked protein 2; DJ79P11.1; hBex2
Rattus norvegicus (Norway rat) : Bex2 (brain expressed X-linked 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bex2 (brain expressed X-linked 2)
Pan paniscus (bonobo/pygmy chimpanzee) : BEX2 (brain expressed X-linked 2)
Canis lupus familiaris (dog) : LOC100684429 (protein BEX1-like)
Sus scrofa (pig) : BEX1 (brain expressed, X-linked 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X103,309,346 - 103,310,990 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X102,564,274 - 102,565,974 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X102,450,930 - 102,452,601 (-)NCBINCBI36hg18NCBI36
Build 34X102,370,419 - 102,372,090NCBI
CeleraX103,003,273 - 103,004,973 (-)NCBI
Cytogenetic MapXq22.2NCBI
HuRefX92,227,655 - 92,229,355 (-)NCBIHuRef
CHM1_1X102,457,260 - 102,458,960 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on BEX2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1353223
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.