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Gene: PDE6H (phosphodiesterase 6H) Homo sapiens
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Symbol: PDE6H
Name: phosphodiesterase 6H
Description: Predicted to have enzyme inhibitor activity. Predicted to be involved in activation of MAPK activity; positive regulation of G protein-coupled receptor signaling pathway; and positive regulation of epidermal growth factor receptor signaling pathway. Predicted to localize to photoreceptor outer segment membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ACHM6; GMP-PDE gamma; phosphodiesterase 6H, cGMP-specific, cone, gamma; RCD3; retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
Orthologs:
Mus musculus (house mouse) : Pde6h (phosphodiesterase 6H, cGMP-specific, cone, gamma)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pde6h (phosphodiesterase 6H)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pde6h (phosphodiesterase 6H)
Pan paniscus (bonobo/pygmy chimpanzee) : PDE6H (phosphodiesterase 6H)
Canis lupus familiaris (dog) : PDE6H (phosphodiesterase 6H)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pde6h (phosphodiesterase 6H)
Sus scrofa (pig) : PDE6H (phosphodiesterase 6H)
Chlorocebus sabaeus (African green monkey) : PDE6H (phosphodiesterase 6H)
Heterocephalus glaber (naked mole-rat) : Pde6h (phosphodiesterase 6H)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1214,973,042 - 14,981,865 (+)EnsemblGRCh38hg38GRCh38
GRCh381214,973,042 - 14,981,865 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371215,125,956 - 15,134,799 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361215,017,245 - 15,026,066 (+)NCBINCBI36hg18NCBI36
Build 341215,017,244 - 15,026,066NCBI
Celera1220,270,954 - 20,279,795 (+)NCBI
Cytogenetic Map12p12.3NCBI
HuRef1214,895,337 - 14,904,178 (+)NCBIHuRef
CHM1_11215,092,057 - 15,100,898 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - uncurated

Genomics

Comparative Map Data
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miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on PDE6H
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1353241
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.