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Gene: WNT5A (Wnt family member 5A) Homo sapiens
Symbol: WNT5A
Name: Wnt family member 5A
Description: Exhibits DNA-binding transcription factor activity; signaling receptor binding activity; and transcription regulatory region DNA binding activity. Involved in several processes, including animal organ development; positive regulation of cytokine production; and positive regulation of macromolecule metabolic process. Localizes to the extracellular space and glutamatergic synapse. Colocalizes with the collagen-containing extracellular matrix. Implicated in autosomal dominant Robinow syndrome 1. Biomarker of endometrial carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: hWNT5A; protein Wnt-5a; wingless-type MMTV integration site family member 5A; wingless-type MMTV integration site family, member 5A; WNT-5A protein
Mus musculus (house mouse) : Wnt5a (wingless-type MMTV integration site family, member 5A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Wnt5a (Wnt family member 5A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wnt5a (Wnt family member 5A)
Pan paniscus (bonobo/pygmy chimpanzee) : WNT5A (Wnt family member 5A)
Canis lupus familiaris (dog) : WNT5A (Wnt family member 5A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wnt5a (Wnt family member 5A)
Sus scrofa (pig) : WNT5A (Wnt family member 5A)
Chlorocebus sabaeus (green monkey) : WNT5A (Wnt family member 5A)
Heterocephalus glaber (naked mole-rat) : Wnt5a (Wnt family member 5A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl355,465,715 - 55,490,539 (-)Ensembl
GRCh38355,465,715 - 55,505,261 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37355,499,743 - 55,521,670 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36355,474,783 - 55,496,371 (-)NCBINCBI36hg18NCBI36
Build 34355,474,783 - 55,496,371NCBI
Celera355,465,957 - 55,488,272 (-)NCBI
Cytogenetic Map3p14.3NCBI
HuRef355,548,623 - 55,570,480 (-)NCBIHuRef
CHM1_1355,451,089 - 55,473,010 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on WNT5A
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1353257
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-02-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.