Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: PCDH11X (protocadherin 11 X-linked) Homo sapiens
Analyze
Symbol: PCDH11X
Name: protocadherin 11 X-linked
Description: This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 7 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene is located in a major X/Y block of homology and its Y homolog, despite divergence leading to coding region changes, is the most closely related cadherin family member. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system. Disruption of this gene may be associated with developmental dyslexia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: PCDH-X; PCDH-Y; PCDH11; PCDH11Y; PCDH22; PCDHX; PCDHY; PPP1R119; protocadherin 11X; protocadherin on the X chromosome; Protocadherin on the Y chromosome; Protocadherin prostate cancer; protocadherin-11 X-linked; Protocadherin-11 Y-linked; Protocadherin-22; Protocadherin-PC; protocadherin-S
Orthologs:
Mus musculus (house mouse) : Pcdh11x (protocadherin 11 X-linked)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pcdh11x (protocadherin 11 X-linked)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pcdh11x (protocadherin 11 X-linked)
Pan paniscus (bonobo/pygmy chimpanzee) : PCDH11X (protocadherin 11 X-linked)
Canis lupus familiaris (dog) : PCDH11X (protocadherin 11 X-linked)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pcdh11x (protocadherin 11 X-linked)
Sus scrofa (pig) : PCDH11X (protocadherin 11 X-linked)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X91,779,310 - 92,623,230 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X91,034,260 - 91,878,229 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X90,920,960 - 91,764,882 (+)NCBINCBI36hg18NCBI36
Build 34X90,895,803 - 91,684,371NCBI
CeleraX91,530,268 - 92,381,817 (+)NCBI
Cytogenetic MapXq21.31NCBI
CHM1_1X90,983,155 - 91,771,164 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
 
More on PCDH11X
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1353305
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.