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Gene: EPHB1 (EPH receptor B1) Homo sapiens
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Symbol: EPHB1
Name: EPH receptor B1
Description: Exhibits transmembrane-ephrin receptor activity. Involved in several processes, including ephrin receptor signaling pathway; protein autophosphorylation; and regulation of MAPK cascade. Localizes to several cellular components, including early endosome membrane; endoplasmic reticulum; and integral component of plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: EK6; ELK; eph tyrosine kinase 2; EPH-like kinase 6; ephrin type-B receptor 1; EPHT2; FLJ37986; Hek6; NET; neuronally-expressed EPH-related tyrosine kinase; soluble EPHB1 variant 1; tyrosine-protein kinase receptor EPH-2
Orthologs:
Mus musculus (house mouse) : Ephb1 (Eph receptor B1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ephb1 (Eph receptor B1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ephb1 (EPH receptor B1)
Pan paniscus (bonobo/pygmy chimpanzee) : EPHB1 (EPH receptor B1)
Canis lupus familiaris (dog) : EPHB1 (EPH receptor B1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ephb1 (EPH receptor B1)
Sus scrofa (pig) : EPHB1 (EPH receptor B1)
Chlorocebus sabaeus (African green monkey) : EPHB1 (EPH receptor B1)
Heterocephalus glaber (naked mole-rat) : Ephb1 (EPH receptor B1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3134,597,801 - 135,260,467 (+)EnsemblGRCh38hg38GRCh38
GRCh383134,595,264 - 135,260,467 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373134,514,099 - 134,979,309 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363135,996,950 - 136,461,999 (+)NCBINCBI36hg18NCBI36
Build 343135,996,957 - 136,462,003NCBI
Celera3132,940,535 - 133,405,242 (+)NCBI
Cytogenetic Map3q22.2NCBI
HuRef3131,890,822 - 132,356,715 (+)NCBIHuRef
CHM1_13134,478,274 - 134,942,745 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on EPHB1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1353347
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.