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Gene: KCNQ1 (potassium voltage-gated channel subfamily Q member 1) Homo sapiens
Symbol: KCNQ1
Name: potassium voltage-gated channel subfamily Q member 1
CRRD ID: 1353354
Description: Exhibits several functions, including calmodulin binding activity; protein kinase A binding activity; and voltage-gated potassium channel activity. Involved in several processes, including ion transmembrane transport; regulation of heart contraction; and regulation of ion transmembrane transport. Localizes to several cellular components, including basolateral plasma membrane; endosome; and membrane raft. Implicated in heart conduction disease (multiple) and long QT syndrome (multiple). Biomarker of seminoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATFB1; ATFB3; FLJ26167; IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1; JLNS1; KCNA8; KCNA9; kidney and cardiac voltage dependend K+ channel; KQT-like 1; Kv1.9; Kv7.1; KVLQT1; LQT; LQT1; potassium channel, voltage gated KQT-like subfamily Q, member 1; potassium voltage-gated channel subfamily KQT member 1; potassium voltage-gated channel, KQT-like subfamily, member 1; RWS; slow delayed rectifier channel subunit; SQT2; voltage-gated potassium channel subunit Kv7.1; WRS
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl112,444,684 - 2,849,105 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl112,444,684 - 2,848,991 (+)EnsemblGRCh38hg38GRCh38
GRCh38112,445,008 - 2,849,110 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37112,466,221 - 2,870,340 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36112,422,797 - 2,826,916 (+)NCBINCBI36hg18NCBI36
Build 34112,439,259 - 2,826,915NCBI
Celera112,501,049 - 2,905,069 (+)NCBI
Cytogenetic Map11p15.5-p15.4NCBI
HuRef112,256,184 - 2,658,673 (+)NCBIHuRef
CHM1_1112,465,155 - 2,869,215 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)