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Gene: CDH3 (cadherin 3) Homo sapiens
Symbol: CDH3
Name: cadherin 3
CRRD ID: 1353368
Description: Predicted to have cadherin binding activity and calcium ion binding activity. Involved in several processes, including negative regulation of timing of catagen; positive regulation of signal transduction; and regulation of gene expression. Localizes to cell junction and plasma membrane. Implicated in congenital hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cadherin 3, type 1, P-cadherin (placental); cadherin-3; calcium-dependent adhesion protein, placental; CDHP; HJMD; PCAD
Mus musculus (house mouse) : Cdh3 (cadherin 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cdh3 (cadherin 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdh3 (cadherin 3)
Pan paniscus (bonobo/pygmy chimpanzee) : CDH3 (cadherin 3)
Canis lupus familiaris (dog) : CDH3 (cadherin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdh3 (cadherin 3)
Sus scrofa (pig) : CDH3 (cadherin 3)
Chlorocebus sabaeus (African green monkey) : CDH3 (cadherin 3)
Heterocephalus glaber (naked mole-rat) : Cdh3 (cadherin 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1668,636,189 - 68,722,616 (+)EnsemblGRCh38hg38GRCh38
GRCh381668,644,914 - 68,727,573 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371668,678,151 - 68,732,959 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361667,236,277 - 67,290,443 (+)NCBINCBI36hg18NCBI36
Build 341667,236,276 - 67,290,442NCBI
Celera1653,187,169 - 53,242,286 (+)NCBI
Cytogenetic Map16q22.1NCBI
HuRef1654,551,120 - 54,605,916 (+)NCBIHuRef
CHM1_11670,086,950 - 70,141,070 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CDH3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1353368
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-10-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.