Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: XIAP (X-linked inhibitor of apoptosis) Homo sapiens
Symbol: XIAP
Name: X-linked inhibitor of apoptosis
Description: Exhibits identical protein binding activity and ubiquitin protein ligase activity. Involved in cellular response to DNA damage stimulus; positive regulation of canonical Wnt signaling pathway; and regulation of cellular protein metabolic process. Localizes to cytoplasm and nucleus. Implicated in X-linked lymphoproliferative syndrome 2 and prostate cancer. Biomarker of breast cancer; breast ductal carcinoma; cervix uteri carcinoma in situ; prostate cancer; and renal cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: API3; apoptosis inhibitor 3; baculoviral IAP repeat-containing protein 4; BIRC4; E3 ubiquitin-protein ligase XIAP; FLJ26913; hIAP-3; hIAP3; IAP-3; IAP-like protein; IAP-like protein 1; ILP1; inhibitor of apoptosis protein 3; MIHA; RING-type E3 ubiquitin transferase XIAP; X-linked IAP; X-linked inhibitor of apoptosis protein; X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase; XLP2
Mus musculus (house mouse) : Xiap (X-linked inhibitor of apoptosis)  MGI  Alliance
Rattus norvegicus (Norway rat) : Xiap (X-linked inhibitor of apoptosis)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Xiap (X-linked inhibitor of apoptosis)
Pan paniscus (bonobo/pygmy chimpanzee) : XIAP (X-linked inhibitor of apoptosis)
Canis lupus familiaris (dog) : XIAP (X-linked inhibitor of apoptosis)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Xiap (X-linked inhibitor of apoptosis)
Sus scrofa (pig) : XIAP (X-linked inhibitor of apoptosis)
Chlorocebus sabaeus (African green monkey) : XIAP (X-linked inhibitor of apoptosis)
more info ...
Related Pseudogenes: XIAPP2   XIAPP3  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 EnsemblX123,859,724 - 123,913,979 (+)EnsemblGRCh38hg38GRCh38
GRCh38X123,859,708 - 123,913,972 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X122,993,662 - 123,047,829 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X122,821,729 - 122,875,503 (+)NCBINCBI36hg18NCBI36
Build 34X122,719,582 - 122,773,357NCBI
CeleraX123,378,893 - 123,432,624 (+)NCBI
Cytogenetic MapXq25NCBI
HuRefX112,377,835 - 112,430,903 (+)NCBIHuRef
CHM1_1X122,904,824 - 122,959,188 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers