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Gene: KDM4D (lysine demethylase 4D) Homo sapiens
Symbol: KDM4D
Name: lysine demethylase 4D
Description: Exhibits histone demethylase activity (H3-K9 specific). Involved in several processes, including histone H3-K9 demethylation; positive regulation of chromatin binding activity; and positive regulation of double-strand break repair via nonhomologous end joining. Localizes to site of double-strand break. Biomarker of nephroblastoma; PARTICIPATES IN histone modification pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-hydroxypropanoic acid; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: [histone H3]-trimethyl-L-lysine(9) demethylase 4D; FLJ10251; jmjC domain-containing histone demethylation protein 3D; JMJD2D; jumonji domain containing 2D; jumonji domain-containing protein 2D; lysine (K)-specific demethylase 4D; lysine-specific demethylase 4D; MGC141909
Mus musculus (house mouse) : Kdm4d (lysine (K)-specific demethylase 4D)  MGI  Alliance
Rattus norvegicus (Norway rat) : Kdm4d (lysine demethylase 4D)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdm4d (lysine demethylase 4D)
Pan paniscus (bonobo/pygmy chimpanzee) : KDM4D (lysine demethylase 4D)
Canis lupus familiaris (dog) : KDM4D (lysine demethylase 4D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdm4d (lysine demethylase 4D)
Sus scrofa (pig) : LOC100627380 (lysine-specific demethylase 4D-like)
Chlorocebus sabaeus (African green monkey) : KDM4D (lysine demethylase 4D)
Heterocephalus glaber (naked mole-rat) : Kdm4d (lysine demethylase 4D)
more info ...
Related Pseudogenes: AP001264.1   AP002383.1   AP002383.5  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1194,973,709 - 94,999,519 (+)EnsemblGRCh38hg38GRCh38
GRCh381194,973,709 - 94,999,519 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371194,706,845 - 94,732,678 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361194,346,493 - 94,372,326 (+)NCBINCBI36hg18NCBI36
Build 341194,346,492 - 94,372,322NCBI
Celera1191,994,632 - 92,020,465 (+)NCBI
Cytogenetic Map11q21NCBI
HuRef1190,771,786 - 90,797,622 (+)NCBIHuRef
CHM1_11194,589,894 - 94,615,685 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on KDM4D
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1353550
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.