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Gene: ASMT (acetylserotonin O-methyltransferase) Homo sapiens
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Symbol: ASMT
Name: acetylserotonin O-methyltransferase
Description: This gene belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: acetylserotonin methyltransferase (Y chromosome); acetylserotonin N-methyltransferase; ASMTY; HIOMT; HIOMTY; hydroxyindole O-methyltransferase
Orthologs:
Mus musculus (house mouse) : Asmt (acetylserotonin O-methyltransferase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Asmt (acetylserotonin O-methyltransferase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Asmt (acetylserotonin O-methyltransferase)
Pan paniscus (bonobo/pygmy chimpanzee) : ASMT (acetylserotonin O-methyltransferase)
Canis lupus familiaris (dog) : ASMT (acetylserotonin O-methyltransferase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Asmt (acetylserotonin O-methyltransferase)
Sus scrofa (pig) : LOC110258194 (acetylserotonin O-methyltransferase-like)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X1,595,455 - 1,643,081 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38Y1,595,455 - 1,643,081 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X1,714,348 - 1,761,974 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh37Y1,664,348 - 1,711,974 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X1,674,348 - 1,721,974 (+)NCBINCBI36hg18NCBI36
Build 36Y1,674,348 - 1,721,974 (+)NCBINCBI36hg18NCBI36
Build 34Y1,758,174 - 1,805,801NCBI
CeleraX5,992,483 - 6,035,986 (+)NCBI
Cytogenetic MapXp22.33 and Yp11.2NCBI
CHM1_1X1,744,907 - 1,789,431 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on ASMT
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1353638
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.