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Gene: MGRN1 (mahogunin ring finger 1) Homo sapiens
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Symbol: MGRN1
Name: mahogunin ring finger 1
Description: Exhibits ubiquitin-protein transferase activity. Involved in endosome to lysosome transport; negative regulation of signal transduction; and protein monoubiquitination. Localizes to the early endosome; nucleus; and plasma membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: E3 ubiquitin-protein ligase MGRN1; KIAA0544; mahogunin ring finger 1, E3 ubiquitin protein ligase; mahogunin RING finger protein 1; mahogunin, ring finger 1; probable E3 ubiquitin-protein ligase MGRN1; RING finger protein 156; RING-type E3 ubiquitin transferase MGRN1; RNF156
Orthologs:
Mus musculus (house mouse) : Mgrn1 (mahogunin, ring finger 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mgrn1 (mahogunin ring finger 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mgrn1 (mahogunin ring finger 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MGRN1 (mahogunin ring finger 1)
Canis lupus familiaris (dog) : MGRN1 (mahogunin ring finger 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mgrn1 (mahogunin ring finger 1)
Sus scrofa (pig) : MGRN1 (mahogunin ring finger 1)
Chlorocebus sabaeus (African green monkey) : MGRN1 (mahogunin ring finger 1)
Heterocephalus glaber (naked mole-rat) : Mgrn1 (mahogunin ring finger 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl164,616,493 - 4,690,974 (+)EnsemblGRCh38hg38GRCh38
GRCh38164,624,824 - 4,690,974 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37164,674,825 - 4,740,975 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36164,614,854 - 4,680,974 (+)NCBINCBI36hg18NCBI36
Build 34164,614,853 - 4,680,972NCBI
Celera164,883,683 - 4,949,753 (+)NCBI
Cytogenetic Map16p13.3NCBI
HuRef164,641,815 - 4,707,494 (+)NCBIHuRef
CHM1_1164,674,882 - 4,741,756 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
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miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on MGRN1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1353673
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.