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Gene: CD27 (CD27 molecule) Homo sapiens
Symbol: CD27
Name: CD27 molecule
Description: Exhibits cysteine-type endopeptidase inhibitor activity involved in apoptotic process. Involved in extrinsic apoptotic signaling pathway and negative regulation of apoptotic process. Predicted to localize to the external side of plasma membrane. Implicated in lymphoproliferative syndrome 2.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD27 antigen; CD27L receptor; MGC20393; S152; S152. LPFS2; T cell activation antigen CD27; T cell activation antigen S152; T-cell activation antigen CD27; T14; TNFRSF7; Tp55; tumor necrosis factor receptor superfamily member 7; tumor necrosis factor receptor superfamily, member 7
Mus musculus (house mouse) : Cd27 (CD27 antigen)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cd27 (CD27 molecule)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd27 (CD27 molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD27 (CD27 molecule)
Canis lupus familiaris (dog) : CD27 (CD27 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd27 (CD27 molecule)
Sus scrofa (pig) : CD27 (CD27 molecule)
Chlorocebus sabaeus (African green monkey) : CD27 (CD27 molecule)
Heterocephalus glaber (naked mole-rat) : Cd27 (CD27 molecule)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl126,444,867 - 6,451,718 (+)Ensembl
GRCh38126,444,867 - 6,451,718 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37126,554,051 - 6,560,884 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,424,312 - 6,431,145 (+)NCBINCBI36hg18NCBI36
Build 34126,424,326 - 6,431,144NCBI
Celera128,170,942 - 8,177,775 (+)NCBI
Cytogenetic Map12p13.31NCBI
HuRef126,408,240 - 6,415,073 (+)NCBIHuRef
CHM1_1126,552,929 - 6,559,762 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on CD27
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1353701
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-01-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.