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Gene: FOXO4 (forkhead box O4) Homo sapiens
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Symbol: FOXO4
Name: forkhead box O4
Description: This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AFX; AFX1; fork head domain transcription factor AFX1; forkhead box protein O4; MGC120490; MLLT7; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila), translocated to, 7; translocated to, 7
Orthologs:
Mus musculus (house mouse) : Foxo4 (forkhead box O4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Foxo4 (forkhead box O4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Foxo4 (forkhead box O4)
Pan paniscus (bonobo/pygmy chimpanzee) : FOXO4 (forkhead box O4)
Canis lupus familiaris (dog) : FOXO4 (forkhead box O4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Foxo4 (forkhead box O4)
Sus scrofa (pig) : FOXO4 (forkhead box O4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X71,096,149 - 71,103,534 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X70,315,999 - 70,323,384 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X70,232,751 - 70,240,109 (+)NCBINCBI36hg18NCBI36
Build 34X70,099,230 - 70,106,405NCBI
CeleraX70,670,001 - 70,677,287 (+)NCBI
Cytogenetic MapXq13.1NCBI
HuRefX64,135,718 - 64,143,103 (+)NCBIHuRef
CHM1_1X70,208,338 - 70,215,723 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on FOXO4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1353756
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.