Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: HES5 (hes family bHLH transcription factor 5) Homo sapiens
Symbol: HES5
Name: hes family bHLH transcription factor 5
CRRD ID: 1353774
Description: Exhibits sequence-specific double-stranded DNA binding activity. Involved in several processes, including negative regulation of stem cell differentiation; neuronal stem cell population maintenance; and positive regulation of smooth muscle cell proliferation. Predicted to localize to nuclear chromatin.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bHLHb38; class B basic helix-loop-helix protein 38; hairy and enhancer of split 5; transcription factor HES-5
Mus musculus (house mouse) : Hes5 (hes family bHLH transcription factor 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hes5 (hes family bHLH transcription factor 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hes5 (hes family bHLH transcription factor 5)
Pan paniscus (bonobo/pygmy chimpanzee) : HES5 (hes family bHLH transcription factor 5)
Canis lupus familiaris (dog) : HES5 (hes family bHLH transcription factor 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hes5 (hes family bHLH transcription factor 5)
Sus scrofa (pig) : HES5 (hes family bHLH transcription factor 5)
Chlorocebus sabaeus (African green monkey) : HES5 (hes family bHLH transcription factor 5)
Heterocephalus glaber (naked mole-rat) : Hes5 (hes family bHLH transcription factor 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl12,528,745 - 2,530,263 (-)EnsemblGRCh38hg38GRCh38
GRCh3812,528,745 - 2,530,554 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712,460,184 - 2,461,684 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612,450,044 - 2,451,544 (-)NCBINCBI36hg18NCBI36
Build 3412,492,347 - 2,493,846NCBI
Celera1124,288 - 125,788 (+)NCBI
Cytogenetic Map1p36.32NCBI
HuRef11,739,123 - 1,740,623 (-)NCBIHuRef
CHM1_112,446,941 - 2,448,441 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on HES5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1353774
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.