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Gene: DEFA4 (defensin alpha 4) Homo sapiens
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Symbol: DEFA4
Name: defensin alpha 4
Description: Exhibits protein homodimerization activity. Involved in several processes, including T cell chemotaxis; antimicrobial humoral immune response mediated by antimicrobial peptide; and defense response to other organism. Localizes to the azurophil granule.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: corticostatin; DEF4; defensin, alpha 4; defensin, alpha 4, corticostatin; defensin, alpha 4, preproprotein; HNP-4; HP-4; HP4; MGC120099; MGC138296; neutrophil defensin 4
Orthologs:
Mus musculus (house mouse) : Defa31 (defensin, alpha, 31)  MGI  Alliance
Rattus norvegicus (Norway rat) : Np4 (defensin NP-4 precursor)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : DEFA4 (defensin alpha 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl86,935,820 - 6,938,306 (-)EnsemblGRCh38hg38GRCh38
GRCh3886,935,820 - 6,938,306 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3786,793,345 - 6,795,786 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3686,780,755 - 6,783,196 (-)NCBINCBI36hg18NCBI36
Build 3486,780,754 - 6,783,196NCBI
Celera86,770,132 - 6,772,573 (-)NCBI
Cytogenetic Map8p23.1NCBI
HuRef86,572,881 - 6,575,322 (-)NCBIHuRef
CHM1_186,882,467 - 6,884,985 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on DEFA4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1353794
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.