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Gene: ALK (ALK receptor tyrosine kinase) Homo sapiens
Symbol: ALK
Name: ALK receptor tyrosine kinase
Description: Exhibits identical protein binding activity and transmembrane receptor protein tyrosine kinase activity. Involved in protein autophosphorylation. Localizes to the integral component of plasma membrane and protein-containing complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ALK tyrosine kinase receptor; anaplastic lymphoma kinase; anaplastic lymphoma kinase (ki-1); anaplastic lymphoma receptor tyrosine kinase; CD246; CD246 antigen; mutant anaplastic lymphoma kinase; NBLST3; TFG/ALK
Mus musculus (house mouse) : Alk (anaplastic lymphoma kinase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Alk (ALK receptor tyrosine kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Alk (ALK receptor tyrosine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : ALK (ALK receptor tyrosine kinase)
Canis lupus familiaris (dog) : ALK (ALK receptor tyrosine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Alk (ALK receptor tyrosine kinase)
Sus scrofa (pig) : ALK (ALK receptor tyrosine kinase)
Chlorocebus sabaeus (green monkey) : ALK (ALK receptor tyrosine kinase)
Heterocephalus glaber (naked mole-rat) : Alk (ALK receptor tyrosine kinase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl229,192,774 - 29,921,586 (-)Ensembl
GRCh38229,190,992 - 29,921,589 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37229,415,640 - 30,144,477 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36229,269,144 - 29,997,936 (-)NCBINCBI36hg18NCBI36
Build 34229,327,292 - 30,056,083NCBI
Celera229,260,042 - 29,988,141 (-)NCBI
Cytogenetic Map2p23.2-p23.1NCBI
HuRef229,156,646 - 29,883,927 (-)NCBIHuRef
CHM1_1229,345,879 - 30,074,503 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants