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Gene: H2AC8 (H2A clustered histone 8) Homo sapiens
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Symbol: H2AC8
Name: H2A clustered histone 8
Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: H2A histone family, member A; H2A.1; H2A.2; H2A/a; H2AFA; HIST1H2AB; HIST1H2AE; histone 1, H2ae; histone cluster 1 H2A family member e; histone cluster 1, H2ae; histone H2A type 1-B/E; histone H2A.2; histone H2A/a; histone H2A/m; histone H2AE
Orthologs:
Mus musculus (house mouse) : H2ac13 (H2A clustered histone 13)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hist1h2af (histone cluster 1 H2A family member F)  Alliance
Canis lupus familiaris (dog) : LOC111093989 (histone H2A type 1-B/E)
Sus scrofa (pig) : LOC110261483 (histone H2A type 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38626,216,920 - 26,217,483 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37626,217,148 - 26,217,711 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36626,325,127 - 26,325,690 (+)NCBINCBI36hg18NCBI36
Build 34626,325,126 - 26,325,690NCBI
Celera627,446,451 - 27,447,014 (+)NCBI
Cytogenetic Map6p22.2NCBI
HuRef626,160,148 - 26,160,711 (+)NCBIHuRef
CHM1_1626,219,309 - 26,219,872 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on H2AC8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1353821
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.