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Gene: H2AC8 (H2A clustered histone 8) Homo sapiens
Symbol: H2AC8
Name: H2A clustered histone 8
Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: H2A histone family, member A; H2A.1; H2A.2; H2A/a; H2AFA; HIST1H2AB; HIST1H2AE; histone 1, H2ae; histone cluster 1 H2A family member e; histone cluster 1, H2ae; histone H2A type 1-B/E; histone H2A.2; histone H2A/a; histone H2A/m; histone H2AE
Mus musculus (house mouse) : H2ac13 (H2A clustered histone 13)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hist1h2af (histone cluster 1 H2A family member F)  Alliance
Canis lupus familiaris (dog) : LOC111093989 (histone H2A type 1-B/E)
Sus scrofa (pig) : LOC110261483 (histone H2A type 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38626,216,920 - 26,217,483 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37626,217,148 - 26,217,711 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36626,325,127 - 26,325,690 (+)NCBINCBI36hg18NCBI36
Build 34626,325,126 - 26,325,690NCBI
Celera627,446,451 - 27,447,014 (+)NCBI
Cytogenetic Map6p22.2NCBI
HuRef626,160,148 - 26,160,711 (+)NCBIHuRef
CHM1_1626,219,309 - 26,219,872 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on H2AC8
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1353821
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.