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Gene: FLT3LG (fms related receptor tyrosine kinase 3 ligand) Homo sapiens
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Symbol: FLT3LG
Name: fms related receptor tyrosine kinase 3 ligand
Description: Predicted to have identical protein binding activity and receptor tyrosine kinase binding activity. Involved in embryonic hemopoiesis and positive regulation of cell population proliferation. Predicted to localize to cell surface and extracellular space. Implicated in colon carcinoma; glioblastoma multiforme; and malignant glioma. Biomarker of Fanconi anemia; aplastic anemia; multiple myeloma; and myelofibrosis.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FL; FLG3L; flt3 ligand; FLT3L; fms related tyrosine kinase 3 ligand; fms-related tyrosine kinase 3 ligand; SL cytokine
Orthologs:
Mus musculus (house mouse) : Flt3l (FMS-like tyrosine kinase 3 ligand)  MGI  Alliance
Rattus norvegicus (Norway rat) : Flt3lg (Fms related receptor tyrosine kinase 3 ligand)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Flt3lg (fms related receptor tyrosine kinase 3 ligand)
Pan paniscus (bonobo/pygmy chimpanzee) : FLT3LG (fms related receptor tyrosine kinase 3 ligand)
Canis lupus familiaris (dog) : FLT3LG (fms related receptor tyrosine kinase 3 ligand)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Flt3lg (fms related receptor tyrosine kinase 3 ligand)
Chlorocebus sabaeus (African green monkey) : FLT3LG (fms related receptor tyrosine kinase 3 ligand)
Heterocephalus glaber (naked mole-rat) : Flt3lg (fms related receptor tyrosine kinase 3 ligand)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1949,474,207 - 49,486,231 (+)EnsemblGRCh38hg38GRCh38
GRCh381949,474,172 - 49,487,037 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371949,977,455 - 49,989,491 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,669,298 - 54,681,300 (+)NCBINCBI36hg18NCBI36
Build 341954,669,297 - 54,681,299NCBI
Celera1946,846,847 - 46,858,811 (+)NCBI
Cytogenetic Map19q13.33NCBI
HuRef1946,355,067 - 46,367,027 (+)NCBIHuRef
CHM1_11949,978,739 - 49,990,762 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on FLT3LG
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1353824
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.