Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: NT5C (5', 3'-nucleotidase, cytosolic) Homo sapiens
Symbol: NT5C
Name: 5', 3'-nucleotidase, cytosolic
Description: Exhibits nucleotidase activity and pyrimidine nucleotide binding activity. Involved in dephosphorylation and pyrimidine deoxyribonucleotide catabolic process. Localizes to the cytosol and nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 5' nucleotidase, deoxy (pyrimidine), cytosolic type C; 5'(3')-deoxyribonucleotidase, cytosolic type; cdN; cytosolic 5',3'-pyrimidine nucleotidase; deoxy-5'-nucleotidase 1; DNT; dNT-1; DNT1; epididymis luminal protein 74; HEL74; P5N2; PN-I; PN-II; UMPH2; uridine 5'-monophosphate phosphohydrolase 2; uridine 5-prime monophosphate hydrolase 2
Mus musculus (house mouse) : Nt5c (5',3'-nucleotidase, cytosolic)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nt5c (5', 3'-nucleotidase, cytosolic)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nt5c (5', 3'-nucleotidase, cytosolic)
Pan paniscus (bonobo/pygmy chimpanzee) : NT5C (5', 3'-nucleotidase, cytosolic)
Canis lupus familiaris (dog) : NT5C (5', 3'-nucleotidase, cytosolic)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nt5c (5', 3'-nucleotidase, cytosolic)
Sus scrofa (pig) : NT5C (5', 3'-nucleotidase, cytosolic)
Chlorocebus sabaeus (African green monkey) : NT5C (5', 3'-nucleotidase, cytosolic)
Heterocephalus glaber (naked mole-rat) : Nt5c (5', 3'-nucleotidase, cytosolic)
more info ...
Related Pseudogenes: NT5CP1   NT5CP2   NT5CP3  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1775,130,225 - 75,131,757 (-)Ensembl
GRCh381775,130,225 - 75,131,965 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371773,126,320 - 73,127,890 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361770,637,918 - 70,639,472 (-)NCBINCBI36hg18NCBI36
Build 341770,637,918 - 70,639,472NCBI
Celera1769,718,700 - 69,720,253 (-)NCBI
Cytogenetic Map17q25.1NCBI
HuRef1768,536,008 - 68,537,577 (-)NCBIHuRef
CHM1_11773,190,820 - 73,192,389 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on NT5C
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1353894
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.