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Gene: MYH10 (myosin heavy chain 10) Homo sapiens
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Symbol: MYH10
Name: myosin heavy chain 10
Description: This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-10 (MYO10). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene have been associated with May-Hegglin anomaly and developmental defects in brain and heart. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cellular myosin heavy chain, type B; cellular myosin heavy chain, type B type B; MGC134913; MGC134914; myosin heavy chain, non-muscle IIb; myosin heavy chain, nonmuscle type B; myosin, heavy chain 10, non-muscle; myosin, heavy polypeptide 10, non-muscle; myosin-10; near to the ATP binding region; NMMHC II-b; NMMHC-B; NMMHC-IIB; NMMHCB; non-muscle myosin heavy chain B; non-muscle myosin heavy chain IIb; nonmuscle myosin heavy chain 10; nonmuscle myosin heavy chain IIB; nonmuscle myosin heavy chain-B; nonmuscle myosin II heavy chain-B
Orthologs:
Mus musculus (house mouse) : Myh10 (myosin, heavy polypeptide 10, non-muscle)  MGI  Alliance
Rattus norvegicus (Norway rat) : Myh10 (myosin heavy chain 10)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Myh10 (myosin heavy chain 10)
Pan paniscus (bonobo/pygmy chimpanzee) : MYH10 (myosin heavy chain 10)
Canis lupus familiaris (dog) : MYH10 (myosin heavy chain 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Myh10 (myosin heavy chain 10)
Sus scrofa (pig) : MYH10 (myosin heavy chain 10)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38178,474,205 - 8,631,369 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37178,377,523 - 8,534,094 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36178,318,255 - 8,474,761 (-)NCBINCBI36hg18NCBI36
Build 34178,318,254 - 8,474,761NCBI
Celera178,408,358 - 8,564,898 (-)NCBI
Cytogenetic Map17p13.1NCBI
HuRef178,276,713 - 8,433,166 (-)NCBIHuRef
CHM1_1178,386,377 - 8,542,853 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on MYH10
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1353980
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.