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Gene: PRKX (protein kinase X-linked) Homo sapiens
Symbol: PRKX
Name: protein kinase X-linked
Description: This gene encodes a serine threonine protein kinase that has similarity to the catalytic subunit of cyclic AMP dependent protein kinases. The encoded protein is developmentally regulated and may be involved in renal epithelial morphogenesis. This protein may also be involved in macrophage and granulocyte maturation. Abnormal recombination between this gene and a related pseudogene on chromosome Y is a frequent cause of sex reversal disorder in XX males and XY females. Pseudogenes of this gene are found on chromosomes X, 15 and Y. [provided by RefSeq, Feb 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cAMP-dependent protein kinase catalytic subunit PRKX; PKX1; protein kinase PKX1; protein kinase X; serine/threonine-protein kinase PRKX
Mus musculus (house mouse) : Prkx (protein kinase, X-linked)  MGI  Alliance
Rattus norvegicus (Norway rat) : Prkx (protein kinase, X-linked)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prkx (protein kinase X-linked)
Pan paniscus (bonobo/pygmy chimpanzee) : PRKX (protein kinase, X-linked)
Canis lupus familiaris (dog) : PRKX (protein kinase X-linked)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prkx (protein kinase X-linked)
Sus scrofa (pig) : PRKX (protein kinase X-linked)
more info ...
Related Pseudogenes: PRKXP1   PRKXP2   PRKY  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X3,604,343 - 3,713,634 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X3,522,384 - 3,631,675 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X3,532,411 - 3,641,661 (-)NCBINCBI36hg18NCBI36
Build 34X3,515,771 - 3,625,010NCBI
CeleraX7,803,269 - 7,912,726 (-)NCBI
Cytogenetic MapXp22.33NCBI
HuRefX1,474,445 - 1,580,609 (-)NCBIHuRef
CHM1_1X3,552,929 - 3,661,974 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PRKX
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1353983
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.