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Gene: VSIG4 (V-set and immunoglobulin domain containing 4) Homo sapiens
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Symbol: VSIG4
Name: V-set and immunoglobulin domain containing 4
Description: This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: complement receptor of the immunoglobulin superfamily; CRIg; Ig superfamily protein; V-set and immunoglobulin domain-containing protein 4; Z39IG
Orthologs:
Mus musculus (house mouse) : Vsig4 (V-set and immunoglobulin domain containing 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Vsig4 (V-set and immunoglobulin domain containing 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vsig4 (V-set and immunoglobulin domain containing 4)
Pan paniscus (bonobo/pygmy chimpanzee) : VSIG4 (V-set and immunoglobulin domain containing 4)
Canis lupus familiaris (dog) : VSIG4 (V-set and immunoglobulin domain containing 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vsig4 (V-set and immunoglobulin domain containing 4)
Sus scrofa (pig) : VSIG4 (V-set and immunoglobulin domain containing 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X66,021,738 - 66,040,125 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X65,241,580 - 65,259,967 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X65,158,305 - 65,176,692 (-)NCBINCBI36hg18NCBI36
Build 34X65,024,600 - 65,042,906NCBI
CeleraX65,588,725 - 65,607,111 (-)NCBI
Cytogenetic MapXq12NCBI
HuRefX59,068,686 - 59,087,663 (-)NCBIHuRef
CHM1_1X65,134,610 - 65,152,555 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on VSIG4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1354021
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-08-06
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.