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Gene: CLTRN (collectrin, amino acid transport regulator) Homo sapiens
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Symbol: CLTRN
Name: collectrin, amino acid transport regulator
Description: This gene encodes a type 1 transmembrane protein that is important for trafficking amino acid transporters to the apical brush border of proximal tubules. The encoded protein binds to amino acid transporters and regulates their expression on the plasma membrane. It also plays a role in controlling insulin exocytosis by regulating formation of the SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) complex in pancreatic beta cells. The extracellular domain of the encoded protein may be cleaved and shed from the plasma membrane specifically in pancreatic beta cells. [provided by RefSeq, Jun 2013]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 0610008J07Rik; collectrin; kidney-specific membrane protein; NX-17; NX17; TMEM27; transmembrane protein 27
Orthologs:
Mus musculus (house mouse) : Cltrn (collectrin, amino acid transport regulator)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cltrn (collectrin, amino acid transport regulator)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cltrn (collectrin, amino acid transport regulator)
Pan paniscus (bonobo/pygmy chimpanzee) : CLTRN (collectrin, amino acid transport regulator)
Canis lupus familiaris (dog) : CLTRN (collectrin, amino acid transport regulator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cltrn (collectrin, amino acid transport regulator)
Sus scrofa (pig) : CLTRN (collectrin, amino acid transport regulator)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X15,627,316 - 15,675,624 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X15,645,439 - 15,683,154 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X15,555,372 - 15,593,075 (-)NCBINCBI36hg18NCBI36
Build 34X15,405,107 - 15,442,811NCBI
CeleraX19,760,931 - 19,798,641 (-)NCBI
Cytogenetic MapXp22.2NCBI
HuRefX13,399,991 - 13,438,249 (-)NCBIHuRef
CHM1_1X15,676,401 - 15,714,121 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CLTRN
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1354044
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.