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Gene: DACH2 (dachshund family transcription factor 2) Homo sapiens
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Symbol: DACH2
Name: dachshund family transcription factor 2
Description: This gene is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly. The encoded protein contains two characteristic dachshund domains: an N-terminal domain responsible for DNA binding and a C-terminal domain responsible for protein-protein interactions. This gene is located on the X chromosome and is subject to inactivation by DNA methylation. The encoded protein may be involved in regulation of organogenesis and myogenesis, and may play a role in premature ovarian failure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: dachshund homolog 2; FLJ31391; MGC138545
Orthologs:
Mus musculus (house mouse) : Dach2 (dachshund family transcription factor 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dach2 (dachshund family transcription factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dach2 (dachshund family transcription factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : DACH2 (dachshund family transcription factor 2)
Canis lupus familiaris (dog) : LOC612847 (dachshund homolog 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dach2 (dachshund family transcription factor 2)
Sus scrofa (pig) : DACH2 (dachshund family transcription factor 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X86,148,451 - 86,832,602 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X85,403,455 - 86,087,605 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X85,290,281 - 85,974,246 (+)NCBINCBI36hg18NCBI36
Build 34X85,209,769 - 85,893,735NCBI
CeleraX85,643,005 - 86,327,361 (+)NCBI
Cytogenetic MapXq21.2NCBI
HuRefX78,980,199 - 79,660,902 (+)NCBIHuRef
CHM1_1X85,297,015 - 85,980,407 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on DACH2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1354112
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.