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Gene: DACH2 (dachshund family transcription factor 2) Homo sapiens
Symbol: DACH2
Name: dachshund family transcription factor 2
Description: This gene is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly. The encoded protein contains two characteristic dachshund domains: an N-terminal domain responsible for DNA binding and a C-terminal domain responsible for protein-protein interactions. This gene is located on the X chromosome and is subject to inactivation by DNA methylation. The encoded protein may be involved in regulation of organogenesis and myogenesis, and may play a role in premature ovarian failure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: dachshund homolog 2; FLJ31391; MGC138545
Mus musculus (house mouse) : Dach2 (dachshund family transcription factor 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dach2 (dachshund family transcription factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dach2 (dachshund family transcription factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : DACH2 (dachshund family transcription factor 2)
Canis lupus familiaris (dog) : LOC612847 (dachshund homolog 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dach2 (dachshund family transcription factor 2)
Sus scrofa (pig) : DACH2 (dachshund family transcription factor 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X86,148,451 - 86,832,602 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X85,403,455 - 86,087,605 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X85,290,281 - 85,974,246 (+)NCBINCBI36hg18NCBI36
Build 34X85,209,769 - 85,893,735NCBI
CeleraX85,643,005 - 86,327,361 (+)NCBI
Cytogenetic MapXq21.2NCBI
HuRefX78,980,199 - 79,660,902 (+)NCBIHuRef
CHM1_1X85,297,015 - 85,980,407 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on DACH2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1354112
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.