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Gene: MED4 (mediator complex subunit 4) Homo sapiens
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Symbol: MED4
Name: mediator complex subunit 4
Description: Exhibits thyroid hormone receptor binding activity and transcription coregulator activity. Involved in positive regulation of transcription, DNA-templated and transcription initiation from RNA polymerase II promoter. Localizes to the mediator complex. Biomarker of cervical cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: activator-recruited cofactor 36 kDa component; ARC36; DRIP36; FLJ10956; HSPC126; mediator of RNA polymerase II transcription subunit 4; mediator of RNA polymerase II transcription, subunit 4 homolog; mediator of rna polymerase ii transcription, subunit 4 homolog (yeast); mediator, 34-kD subunit, homolog; p36 TRAP/SMCC/PC2 subunit; RP11-90M2.2; TRAP/SMCC/PC2 subunit p36; TRAP/SMCC/PC2 subunit p36 subunit; TRAP36; VDRIP; vitamin D receptor interacting protein; vitamin D receptor-interacting protein, 36-kD; vitamin D3 receptor-interacting protein complex 36 kDa component
Orthologs:
Mus musculus (house mouse) : Med4 (mediator complex subunit 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Med4 (mediator complex subunit 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Med4 (mediator complex subunit 4)
Pan paniscus (bonobo/pygmy chimpanzee) : MED4 (mediator complex subunit 4)
Canis lupus familiaris (dog) : MED4 (mediator complex subunit 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Med4 (mediator complex subunit 4)
Sus scrofa (pig) : MED4 (mediator complex subunit 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381348,075,724 - 48,095,141 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371348,649,864 - 48,669,277 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361347,548,093 - 47,567,241 (-)NCBINCBI36hg18NCBI36
Build 341347,548,092 - 47,567,241NCBI
Celera1329,704,843 - 29,723,982 (-)NCBI
Cytogenetic Map13q14.2NCBI
HuRef1329,441,920 - 29,461,323 (-)NCBIHuRef
CHM1_11348,617,590 - 48,636,992 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on MED4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1354139
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.