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Gene: MED4 (mediator complex subunit 4) Homo sapiens
Symbol: MED4
Name: mediator complex subunit 4
Description: Exhibits thyroid hormone receptor binding activity and transcription coregulator activity. Involved in positive regulation of transcription, DNA-templated and transcription initiation from RNA polymerase II promoter. Localizes to the mediator complex. Biomarker of cervical cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: activator-recruited cofactor 36 kDa component; ARC36; DRIP36; FLJ10956; HSPC126; mediator of RNA polymerase II transcription subunit 4; mediator of RNA polymerase II transcription, subunit 4 homolog; mediator of rna polymerase ii transcription, subunit 4 homolog (yeast); mediator, 34-kD subunit, homolog; p36 TRAP/SMCC/PC2 subunit; RP11-90M2.2; TRAP/SMCC/PC2 subunit p36; TRAP/SMCC/PC2 subunit p36 subunit; TRAP36; VDRIP; vitamin D receptor interacting protein; vitamin D receptor-interacting protein, 36-kD; vitamin D3 receptor-interacting protein complex 36 kDa component
Mus musculus (house mouse) : Med4 (mediator complex subunit 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Med4 (mediator complex subunit 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Med4 (mediator complex subunit 4)
Pan paniscus (bonobo/pygmy chimpanzee) : MED4 (mediator complex subunit 4)
Canis lupus familiaris (dog) : MED4 (mediator complex subunit 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Med4 (mediator complex subunit 4)
Sus scrofa (pig) : MED4 (mediator complex subunit 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381348,075,724 - 48,095,141 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371348,649,864 - 48,669,277 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361347,548,093 - 47,567,241 (-)NCBINCBI36hg18NCBI36
Build 341347,548,092 - 47,567,241NCBI
Celera1329,704,843 - 29,723,982 (-)NCBI
Cytogenetic Map13q14.2NCBI
HuRef1329,441,920 - 29,461,323 (-)NCBIHuRef
CHM1_11348,617,590 - 48,636,992 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on MED4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1354139
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.