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Gene: TNC (tenascin C) Homo sapiens
Symbol: TNC
Name: tenascin C
Description: Exhibits syndecan binding activity. Involved in response to wounding. Localizes to several cellular components, including the collagen-containing extracellular matrix; extracellular space; and focal adhesion. Implicated in allergic conjunctivitis; asthma; and autosomal dominant nonsyndromic deafness 56. Biomarker of several diseases, including glioblastoma multiforme; intracranial vasospasm; lung disease (multiple); pleural disease (multiple); and pulmonary hypertension.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 150-225; cytotactin; deafness, autosomal dominant 56; DFNA56; glioma-associated-extracellular matrix antigen; GMEM; GP; GP 150-225; hexabrachion (tenascin); HXB; JI; MGC167029; myotendinous antigen; neuronectin; tenascin; tenascin-C; tenascin-C additional domain 1; tenascin-C isoform 14/AD1/16; TN; TN-C
Mus musculus (house mouse) : Tnc (tenascin C)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tnc (tenascin C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnc (tenascin C)
Pan paniscus (bonobo/pygmy chimpanzee) : TNC (tenascin C)
Canis lupus familiaris (dog) : TNC (tenascin C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnc (tenascin C)
Sus scrofa (pig) : TNC (tenascin C)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh389115,019,575 - 115,118,244 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh379117,781,854 - 117,880,536 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369116,822,626 - 116,920,307 (-)NCBINCBI36hg18NCBI36
Build 349114,862,366 - 114,959,993NCBI
Celera988,430,273 - 88,527,747 (-)NCBI
Cytogenetic Map9q33.1NCBI
HuRef987,386,539 - 87,484,951 (-)NCBIHuRef
CHM1_19117,928,574 - 118,027,020 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on TNC
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1354144
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.