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Gene: LRCH2 (leucine rich repeats and calponin homology domain containing 2) Homo sapiens
Symbol: LRCH2
Name: leucine rich repeats and calponin homology domain containing 2
Description: This gene encodes a member of the leucine-rich repeat and calponin homology domain-containing protein family. These family members contain multiple N-terminal leucine-rich repeats, in addition to a C-terminal calponin homology domain, a type of domain that mediates interactions with actin filaments. These proteins are conserved across animal species, and studies of a similar Drosophila protein indicate a function as a cytoskeletal scaffolding protein. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: dA204F4.4; KIAA1495; leucine-rich repeat and calponin homology domain-containing protein 2; leucine-rich repeats and calponin homology (CH) domain containing 2; MGC150671
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X115,110,611 - 115,234,082 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X114,345,179 - 114,468,635 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X114,251,435 - 114,374,891 (-)NCBINCBI36hg18NCBI36
Build 34X114,168,161 - 114,291,615NCBI
CeleraX114,780,355 - 114,903,805 (-)NCBI
Cytogenetic MapXq23NCBI
HuRefX103,930,501 - 104,053,588 (-)NCBIHuRef
CHM1_1X114,256,054 - 114,379,667 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on LRCH2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1354195
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-08-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.