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Gene: RALA (RAS like proto-oncogene A) Homo sapiens
Symbol: RALA
Name: RAS like proto-oncogene A
Description: Exhibits several functions, including Edg-2 lysophosphatidic acid receptor binding activity; enzyme binding activity; and purine ribonucleoside binding activity. Involved in several processes, including actin cytoskeleton reorganization; membrane raft localization; and positive regulation of filopodium assembly. Localizes to the cell surface; cleavage furrow; and focal adhesion. Colocalizes with the endocytic vesicle. Biomarker of pancreatic ductal adenocarcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MGC48949; RAL; RALA Ras like proto-oncogene A; Ras family small GTP binding protein RALA; ras related GTP binding protein A; RAS-like protein A; ras-related protein Ral-A; v-ral simian leukemia viral oncogene homolog A (ras related)
Mus musculus (house mouse) : Rala (v-ral simian leukemia viral oncogene A (ras related))  MGI  Alliance
Rattus norvegicus (Norway rat) : Rala (RAS like proto-oncogene A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rala (RAS like proto-oncogene A)
Pan paniscus (bonobo/pygmy chimpanzee) : RALA (RAS like proto-oncogene A)
Canis lupus familiaris (dog) : RALA (RAS like proto-oncogene A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rala (RAS like proto-oncogene A)
Sus scrofa (pig) : RALA (RAS like proto-oncogene A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38739,622,955 - 39,708,124 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37739,663,152 - 39,747,723 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36739,629,687 - 39,714,244 (+)NCBINCBI36hg18NCBI36
Build 34739,436,401 - 39,520,955NCBI
Celera739,650,672 - 39,735,235 (+)NCBI
Cytogenetic Map7p14.1NCBI
HuRef739,547,203 - 39,631,708 (+)NCBIHuRef
CHM1_1739,665,812 - 39,750,388 (+)NCBICHM1_1
CRA_TCAGchr7v2739,701,014 - 39,785,596 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RALA
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1354223
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.