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Gene: RALA (RAS like proto-oncogene A) Homo sapiens
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Symbol: RALA
Name: RAS like proto-oncogene A
Description: Exhibits several functions, including Edg-2 lysophosphatidic acid receptor binding activity; enzyme binding activity; and purine ribonucleoside binding activity. Involved in several processes, including actin cytoskeleton reorganization; membrane raft localization; and positive regulation of filopodium assembly. Localizes to the cell surface; cleavage furrow; and focal adhesion. Colocalizes with the endocytic vesicle. Biomarker of pancreatic ductal adenocarcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MGC48949; RAL; RALA Ras like proto-oncogene A; Ras family small GTP binding protein RALA; ras related GTP binding protein A; RAS-like protein A; ras-related protein Ral-A; v-ral simian leukemia viral oncogene homolog A (ras related)
Orthologs:
Mus musculus (house mouse) : Rala (v-ral simian leukemia viral oncogene A (ras related))  MGI  Alliance
Rattus norvegicus (Norway rat) : Rala (RAS like proto-oncogene A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rala (RAS like proto-oncogene A)
Pan paniscus (bonobo/pygmy chimpanzee) : RALA (RAS like proto-oncogene A)
Canis lupus familiaris (dog) : RALA (RAS like proto-oncogene A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rala (RAS like proto-oncogene A)
Sus scrofa (pig) : RALA (RAS like proto-oncogene A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38739,622,955 - 39,708,124 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37739,663,152 - 39,747,723 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36739,629,687 - 39,714,244 (+)NCBINCBI36hg18NCBI36
Build 34739,436,401 - 39,520,955NCBI
Celera739,650,672 - 39,735,235 (+)NCBI
Cytogenetic Map7p14.1NCBI
HuRef739,547,203 - 39,631,708 (+)NCBIHuRef
CHM1_1739,665,812 - 39,750,388 (+)NCBICHM1_1
CRA_TCAGchr7v2739,701,014 - 39,785,596 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on RALA
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1354223
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.