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Gene: EGFL6 (EGF like domain multiple 6) Homo sapiens
Symbol: EGFL6
Name: EGF like domain multiple 6
Description: This gene encodes a member of the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle, proliferation, and developmental processes. The gene product contains a signal peptide, suggesting that it is secreted; an EGF repeat region consisting of 4 complete EGF-like repeats and 1 partial EGF-like repeat, 3 of which have a calcium-binding consensus sequence; an arg-gly-asp integrin association motif; and a MAM domain, which is believed to have an adhesive function. This gene is expressed early during development, and its expression has been detected in lung and meningioma tumors. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp564P2063; EGF repeat-containing protein 6; EGF-like protein 6; EGF-like-domain, multiple 6; epidermal growth factor-like protein 6; MAEG; MAM and EGF domain containing; MAM and EGF domains-containing gene protein; W80
Mus musculus (house mouse) : Egfl6 (EGF-like-domain, multiple 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Egfl6 (EGF-like-domain, multiple 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Egfl6 (EGF like domain multiple 6)
Pan paniscus (bonobo/pygmy chimpanzee) : EGFL6 (EGF like domain multiple 6)
Canis lupus familiaris (dog) : EGFL6 (EGF like domain multiple 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Egfl6 (EGF like domain multiple 6)
Sus scrofa (pig) : EGFL6 (EGF like domain multiple 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X13,569,575 - 13,633,575 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X13,587,694 - 13,651,694 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X13,497,662 - 13,561,615 (+)NCBINCBI36hg18NCBI36
Build 34X13,347,397 - 13,411,350NCBI
CeleraX17,704,800 - 17,768,780 (+)NCBI
Cytogenetic MapXp22.2NCBI
HuRefX11,346,706 - 11,404,147 (+)NCBIHuRef
CHM1_1X13,618,522 - 13,682,553 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on EGFL6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1354247
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.