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Gene: BRWD3 (bromodomain and WD repeat domain containing 3) Homo sapiens
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Symbol: BRWD3
Name: bromodomain and WD repeat domain containing 3
Description: The protein encoded by this gene contains a bromodomain and several WD repeats. It is thought to have a chromatin-modifying function, and may thus play a role in transcription. Mutations in this gene are associated with a spectrum of cognitive disabilities and X-linked macrocephaly. This gene is also associated with translocations in patients with B-cell chronic lymphocytic leukemia. [provided by RefSeq, Jul 2017]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BRODL; bromo domain-containing protein disrupted in leukemia; bromodomain and WD repeat-containing protein 3; FLJ33254; FLJ38568; MRX93; novel WD repeat domain protein
Orthologs:
Mus musculus (house mouse) : Brwd3 (bromodomain and WD repeat domain containing 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Brwd3 (bromodomain and WD repeat domain containing 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Brwd3 (bromodomain and WD repeat domain containing 3)
Pan paniscus (bonobo/pygmy chimpanzee) : BRWD3 (bromodomain and WD repeat domain containing 3)
Canis lupus familiaris (dog) : BRWD3 (bromodomain and WD repeat domain containing 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Brwd3 (bromodomain and WD repeat domain containing 3)
Sus scrofa (pig) : BRWD3 (bromodomain and WD repeat domain containing 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X80,669,503 - 80,809,877 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X79,924,987 - 80,065,233 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X79,818,339 - 79,951,889 (-)NCBINCBI36hg18NCBI36
Build 34X79,737,839 - 79,871,378NCBI
CeleraX80,165,105 - 80,305,366 (-)NCBI
Cytogenetic MapXq21.1NCBI
HuRefX73,504,976 - 73,645,667 (-)NCBIHuRef
CHM1_1X79,818,407 - 79,958,670 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on BRWD3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1354337
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-08
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.