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Gene: BRWD3 (bromodomain and WD repeat domain containing 3) Homo sapiens
Symbol: BRWD3
Name: bromodomain and WD repeat domain containing 3
Description: The protein encoded by this gene contains a bromodomain and several WD repeats. It is thought to have a chromatin-modifying function, and may thus play a role in transcription. Mutations in this gene are associated with a spectrum of cognitive disabilities and X-linked macrocephaly. This gene is also associated with translocations in patients with B-cell chronic lymphocytic leukemia. [provided by RefSeq, Jul 2017]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BRODL; bromo domain-containing protein disrupted in leukemia; bromodomain and WD repeat-containing protein 3; FLJ33254; FLJ38568; MRX93; novel WD repeat domain protein
Mus musculus (house mouse) : Brwd3 (bromodomain and WD repeat domain containing 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Brwd3 (bromodomain and WD repeat domain containing 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Brwd3 (bromodomain and WD repeat domain containing 3)
Pan paniscus (bonobo/pygmy chimpanzee) : BRWD3 (bromodomain and WD repeat domain containing 3)
Canis lupus familiaris (dog) : BRWD3 (bromodomain and WD repeat domain containing 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Brwd3 (bromodomain and WD repeat domain containing 3)
Sus scrofa (pig) : BRWD3 (bromodomain and WD repeat domain containing 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X80,669,503 - 80,809,877 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X79,924,987 - 80,065,233 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X79,818,339 - 79,951,889 (-)NCBINCBI36hg18NCBI36
Build 34X79,737,839 - 79,871,378NCBI
CeleraX80,165,105 - 80,305,366 (-)NCBI
Cytogenetic MapXq21.1NCBI
HuRefX73,504,976 - 73,645,667 (-)NCBIHuRef
CHM1_1X79,818,407 - 79,958,670 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on BRWD3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1354337
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.