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Gene: RTKN (rhotekin) Homo sapiens
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Symbol: RTKN
Name: rhotekin
Description: Exhibits GTP-Rho binding activity and GTPase inhibitor activity. Involved in Rho protein signal transduction and regulation of apoptotic process. Predicted to localize to actomyosin contractile ring. Biomarker of hepatocellular carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Orthologs:
Mus musculus (house mouse) : Rtkn (rhotekin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rtkn (rhotekin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rtkn (rhotekin)
Pan paniscus (bonobo/pygmy chimpanzee) : RTKN (rhotekin)
Canis lupus familiaris (dog) : RTKN (rhotekin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rtkn (rhotekin)
Sus scrofa (pig) : RTKN (rhotekin)
Chlorocebus sabaeus (African green monkey) : RTKN (rhotekin)
Heterocephalus glaber (naked mole-rat) : Rtkn (rhotekin)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl274,425,835 - 74,442,422 (-)EnsemblGRCh38hg38GRCh38
GRCh38274,425,835 - 74,441,937 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37274,652,988 - 74,669,060 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36274,506,496 - 74,522,568 (-)NCBINCBI36hg18NCBI36
Build 34274,564,665 - 74,578,602NCBI
Celera274,484,177 - 74,500,249 (-)NCBI
Cytogenetic Map2p13.1NCBI
HuRef274,389,300 - 74,405,372 (-)NCBIHuRef
CHM1_1274,582,406 - 74,598,477 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on RTKN
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1354382
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.