Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: RFX4 (regulatory factor X4) Homo sapiens
Symbol: RFX4
Name: regulatory factor X4
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to localize to the nuclear chromatin.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: NYD-SP10; regulatory factor X 4; regulatory factor X, 4 (influences HLA class II expression); regulatory factor X4, isoform c; testis development protein NYD-SP10; transcription factor NYD-sp10; transcription factor RFX4; winged-helix transcription factor RFX4
Mus musculus (house mouse) : Rfx4 (regulatory factor X, 4 (influences HLA class II expression))  MGI  Alliance
Rattus norvegicus (Norway rat) : Rfx4 (regulatory factor X4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rfx4 (regulatory factor X4)
Pan paniscus (bonobo/pygmy chimpanzee) : RFX4 (regulatory factor X4)
Canis lupus familiaris (dog) : RFX4 (regulatory factor X4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rfx4 (regulatory factor X4)
Sus scrofa (pig) : RFX4 (regulatory factor X4)
Chlorocebus sabaeus (African green monkey) : RFX4 (regulatory factor X4)
Heterocephalus glaber (naked mole-rat) : Rfx4 (regulatory factor X4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl12106,582,907 - 106,762,803 (+)EnsemblGRCh38hg38GRCh38
GRCh3812106,583,004 - 106,762,803 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712106,976,685 - 107,156,582 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612105,501,163 - 105,680,711 (+)NCBINCBI36hg18NCBI36
Build 3412105,479,499 - 105,659,047NCBI
Celera12106,642,624 - 106,822,170 (+)NCBI
Cytogenetic Map12q23.3NCBI
HuRef12104,036,963 - 104,216,955 (+)NCBIHuRef
CHM1_112106,942,490 - 107,122,407 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RFX4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1354416
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.