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Gene: ONECUT2 (one cut homeobox 2) Homo sapiens
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Symbol: ONECUT2
Name: one cut homeobox 2
Description: This gene encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: hepatocyte nuclear factor 6-beta; HNF-6-beta; MGC120377; MGC120378; OC-2; OC2; one cut domain family member 2; one cut domain, family member 2; onecut 2; ONECUT-2 homeodomain transcription factor; transcription factor ONECUT-2
Orthologs:
Mus musculus (house mouse) : Onecut2 (one cut domain, family member 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Onecut2 (one cut homeobox 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Onecut2 (one cut homeobox 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ONECUT2 (one cut homeobox 2)
Canis lupus familiaris (dog) : ONECUT2 (one cut homeobox 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Onecut2 (one cut homeobox 2)
Sus scrofa (pig) : ONECUT2 (one cut homeobox 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381857,435,374 - 57,491,298 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371855,102,917 - 55,158,530 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361853,253,915 - 53,309,528 (+)NCBINCBI36hg18NCBI36
Build 341853,253,914 - 53,295,062NCBI
Celera1851,819,929 - 51,875,634 (+)NCBI
Cytogenetic Map18q21.31NCBI
HuRef1851,813,575 - 51,869,027 (+)NCBIHuRef
CHM1_11855,098,361 - 55,153,854 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on ONECUT2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1354460
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.