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Gene: KDM6A (lysine demethylase 6A) Homo sapiens
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Symbol: KDM6A
Name: lysine demethylase 6A
Description: This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2014]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bA386N14.2; bA386N14.2 (ubiquitously transcribed X chromosome tetratricopeptide repeat protein (UTX)); DKFZp686A03225; histone demethylase UTX; KABUK2; lysine (K)-specific demethylase 6A; lysine-specific demethylase 6A; MGC141941; ubiquitously transcribed tetratricopeptide repeat protein X-linked; ubiquitously transcribed TPR protein on the X chromosome; ubiquitously transcribed X chromosome tetratricopeptide repeat protein; ubiquitously-transcribed TPR gene on the X chromosome; ubiquitously-transcribed TPR protein on the X chromosome; ubiquitously-transcribed X chromosome tetratricopeptide repeat protein; UTX
Orthologs:
Mus musculus (house mouse) : Kdm6a (lysine (K)-specific demethylase 6A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Kdm6a (lysine demethylase 6A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdm6a (lysine demethylase 6A)
Pan paniscus (bonobo/pygmy chimpanzee) : KDM6A (lysine demethylase 6A)
Canis lupus familiaris (dog) : KDM6A (lysine demethylase 6A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdm6a (lysine demethylase 6A)
Sus scrofa (pig) : KDM6A (lysine demethylase 6A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X44,873,175 - 45,112,612 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X44,732,419 - 44,972,024 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X44,617,725 - 44,856,791 (+)NCBINCBI36hg18NCBI36
Build 34X44,489,034 - 44,728,097NCBI
CeleraX48,869,187 - 49,108,532 (+)NCBI
Cytogenetic MapXp11.3NCBI
HuRefX42,453,849 - 42,692,064 (+)NCBIHuRef
CHM1_1X44,765,275 - 45,004,750 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on KDM6A
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1354488
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-07-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.