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Gene: CSF2 (colony stimulating factor 2) Homo sapiens
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Symbol: CSF2
Name: colony stimulating factor 2
Description: Exhibits cytokine activity. Involved in several processes, including cellular response to granulocyte macrophage colony-stimulating factor stimulus; myeloid leukocyte differentiation; and positive regulation of macromolecule metabolic process. Localizes to the extracellular space and intracellular membrane-bounded organelle. Implicated in acute myeloid leukemia; juvenile myelomonocytic leukemia; neutropenia; pulmonary alveolar proteinosis; and visceral leishmaniasis. Biomarker of asthma; chronic obstructive pulmonary disease; and temporal arteritis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: colony stimulating factor 2 (granulocyte-macrophage); colony-stimulating factor; CSF; GMCSF; granulocyte macrophage-colony stimulating factor; granulocyte-macrophage colony stimulating factor; granulocyte-macrophage colony-stimulating factor; MGC131935; MGC138897; molgramostim; molgramostin; sargramostim
Orthologs:
Mus musculus (house mouse) : Csf2 (colony stimulating factor 2 (granulocyte-macrophage))  MGI  Alliance
Rattus norvegicus (Norway rat) : Csf2 (colony stimulating factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Csf2 (colony stimulating factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CSF2 (colony stimulating factor 2)
Canis lupus familiaris (dog) : CSF2 (colony stimulating factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Csf2 (colony stimulating factor 2)
Sus scrofa (pig) : CSF2 (colony stimulating factor 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl5132,073,789 - 132,076,170 (+)Ensembl
GRCh385132,073,789 - 132,076,170 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh375131,409,485 - 131,411,863 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365131,437,384 - 131,439,758 (+)NCBINCBI36hg18NCBI36
Build 345131,437,383 - 131,439,758NCBI
Celera5127,539,561 - 127,541,935 (+)NCBI
Cytogenetic Map5q31.1NCBI
HuRef5126,601,846 - 126,604,224 (+)NCBIHuRef
CHM1_15130,842,312 - 130,844,690 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CSF2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1354508
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.