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Gene: RAB8A (RAB8A, member RAS oncogene family) Homo sapiens
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Symbol: RAB8A
Name: RAB8A, member RAS oncogene family
Description: Exhibits GTPase activity; myosin V binding activity; and purine ribonucleoside binding activity. Involved in several processes, including Golgi vesicle fusion to target membrane; cilium assembly; and vesicle docking involved in exocytosis. Localizes to several cellular components, including the centrosome; cytoplasmic vesicle; and midbody.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MEL; mel transforming oncogene (derived from cell line NK14); mel transforming oncogene (derived from cell line NK14)- RAB8 homolog; mel transforming oncogene (RAB8 homolog); oncogene c-mel; RAB8; ras-associated protein RAB8; ras-related protein Rab-8A
Orthologs:
Mus musculus (house mouse) : Rab8a (RAB8A, member RAS oncogene family)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rab8a (RAB8A, member RAS oncogene family)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rab8a (RAB8A, member RAS oncogene family)
Pan paniscus (bonobo/pygmy chimpanzee) : RAB8A (RAB8A, member RAS oncogene family)
Canis lupus familiaris (dog) : RAB8A (RAB8A, member RAS oncogene family)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rab8a (RAB8A, member RAS oncogene family)
Sus scrofa (pig) : RAB8A (RAB8A, member RAS oncogene family)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381916,111,889 - 16,134,234 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371916,222,490 - 16,244,445 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361916,083,490 - 16,105,445 (+)NCBINCBI36hg18NCBI36
Build 341916,083,489 - 16,105,443NCBI
Celera1916,124,417 - 16,146,398 (+)NCBI
Cytogenetic Map19p13.11NCBI
HuRef1915,793,443 - 15,815,391 (+)NCBIHuRef
CHM1_11916,221,978 - 16,243,940 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on RAB8A
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1354512
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.