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Gene: RAB8A (RAB8A, member RAS oncogene family) Homo sapiens
Symbol: RAB8A
Name: RAB8A, member RAS oncogene family
Description: Exhibits GTPase activity; myosin V binding activity; and purine ribonucleoside binding activity. Involved in several processes, including Golgi vesicle fusion to target membrane; cilium assembly; and vesicle docking involved in exocytosis. Localizes to several cellular components, including the centrosome; cytoplasmic vesicle; and midbody.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MEL; mel transforming oncogene (derived from cell line NK14); mel transforming oncogene (derived from cell line NK14)- RAB8 homolog; mel transforming oncogene (RAB8 homolog); oncogene c-mel; RAB8; ras-associated protein RAB8; ras-related protein Rab-8A
Mus musculus (house mouse) : Rab8a (RAB8A, member RAS oncogene family)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rab8a (RAB8A, member RAS oncogene family)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rab8a (RAB8A, member RAS oncogene family)
Pan paniscus (bonobo/pygmy chimpanzee) : RAB8A (RAB8A, member RAS oncogene family)
Canis lupus familiaris (dog) : RAB8A (RAB8A, member RAS oncogene family)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rab8a (RAB8A, member RAS oncogene family)
Sus scrofa (pig) : RAB8A (RAB8A, member RAS oncogene family)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381916,111,889 - 16,134,234 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371916,222,490 - 16,244,445 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361916,083,490 - 16,105,445 (+)NCBINCBI36hg18NCBI36
Build 341916,083,489 - 16,105,443NCBI
Celera1916,124,417 - 16,146,398 (+)NCBI
Cytogenetic Map19p13.11NCBI
HuRef1915,793,443 - 15,815,391 (+)NCBIHuRef
CHM1_11916,221,978 - 16,243,940 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on RAB8A
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1354512
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.