Gene: Tmco1 (transmembrane and coiled-coil domains 1) Rattus norvegicus
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Symbol: Tmco1
Name: transmembrane and coiled-coil domains 1
Description: Predicted to have calcium channel activity; predicted to be involved in ER overload response, calcium ion transmembrane transport, and endoplasmic reticulum calcium ion homeostasis; predicted to localize to the integral component of endoplasmic reticulum membrane; orthologous to human TMCO1 (transmembrane and coiled-coil domains 1); INTERACTS WITH 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil; amiodarone.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: calcium load-activated calcium channel; CLAC channel; meg-2-like protein; MGC109554; putative membrane protein; transmembrane and coiled-coil domain-containing protein 1; transmembrane and coiled-coil domains protein 1
Orthologs:
Homo sapiens (human) : TMCO1 (transmembrane and coiled-coil domains 1)  HGNC  Alliance
Mus musculus (house mouse) : Tmco1 (transmembrane and coiled-coil domains 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tmco1 (transmembrane and coiled-coil domains 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TMCO1 (transmembrane and coiled-coil domains 1)
Canis lupus familiaris (dog) : TMCO1 (transmembrane and coiled-coil domains 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tmco1 (transmembrane and coiled-coil domains 1)
Sus scrofa (pig) : TMCO1 (transmembrane and coiled-coil domains 1)
more info ...
Allele / Splice: Tmco1Tn(sb-T2/Bart3)2.135Mcwi  
Genetic Models: F344-Tmco1Tn(sb-T2/Bart3)2.135Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01385,465,015 - 85,559,113 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01390,201,608 - 90,202,246 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01390,108,152 - 90,131,984 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41382,971,926 - 82,995,262 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11382,986,113 - 83,009,449 (+)NCBI
Celera1379,165,552 - 79,188,922 (+)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Tmco1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1359178
Created: 2005-07-29
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.