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Gene: Txndc2 (thioredoxin domain containing 2) Rattus norvegicus
Symbol: Txndc2
Name: thioredoxin domain containing 2
Description: Predicted to have protein disulfide isomerase activity and thioredoxin-disulfide reductase activity. Predicted to be involved in cellular response to reactive oxygen species and flagellated sperm motility. Localizes to the outer dense fiber. Orthologous to human TXNDC2 (thioredoxin domain containing 2); INTERACTS WITH bisphenol A; 4,4'-diaminodiphenylmethane (ortholog); aflatoxin B1 (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC94320; similar to spermatid-specific thioredoxin; spermatid-specific thioredoxin-1; sptrx-1; thioredoxin domain containing 2 (spermatozoa); thioredoxin domain-containing protein 2
Homo sapiens (human) : TXNDC2 (thioredoxin domain containing 2)  HGNC  Alliance
Mus musculus (house mouse) : Txndc2 (thioredoxin domain containing 2 (spermatozoa))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Txndc2 (thioredoxin domain containing 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TXNDC2 (thioredoxin domain containing 2)
Canis lupus familiaris (dog) : TXNDC2 (thioredoxin domain containing 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Txndc2 (thioredoxin domain containing 2)
Sus scrofa (pig) : TXNDC2 (thioredoxin domain containing 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.09113,354,047 - 113,358,558 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.09112,886,277 - 112,890,798 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.49104,391,636 - 104,396,147 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.19104,601,119 - 104,605,609 (-)NCBI
Celera9102,617,140 - 102,621,651 (-)NCBICelera
Cytogenetic Map9q37NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Txndc2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1359251
Created: 2005-07-29
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.