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Gene: Oas3 (2'-5'-oligoadenylate synthetase 3) Rattus norvegicus
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Symbol: Oas3
Name: 2'-5'-oligoadenylate synthetase 3
Description: Predicted to have 2'-5'-oligoadenylate synthetase activity; ATP binding activity; and double-stranded RNA binding activity. Predicted to be involved in defense response to virus; negative regulation of viral genome replication; and regulation of ribonuclease activity. Predicted to localize to the cytosol; nucleoplasm; and plasma membrane. Orthologous to human OAS3 (2'-5'-oligoadenylate synthetase 3); PARTICIPATES IN hepatitis C pathway; influenza A pathway; measles pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; bisphenol A; tetrachloromethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: (2-5')oligo(A) synthase 3; 2 ' -5 ' -oligoadenylate synthetase 3; 2'-5'-oligoadenylate synthase 3; 2-5A synthase 3
Orthologs:
Homo sapiens (human) : OAS3 (2'-5'-oligoadenylate synthetase 3)  HGNC  Alliance
Mus musculus (house mouse) : Oas3 (2'-5' oligoadenylate synthetase 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Oas3 (2'-5'-oligoadenylate synthetase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : OAS3 (2'-5'-oligoadenylate synthetase 3)
Canis lupus familiaris (dog) : OAS3 (2'-5'-oligoadenylate synthetase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101966357 (2'-5'-oligoadenylate synthase 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01241,313,081 - 41,368,217 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1241,316,764 - 41,336,562 (+)Ensembl
Rnor_5.01243,148,698 - 43,225,332 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.11236,788,800 - 36,789,002 (+)NCBI
Celera1237,441,178 - 37,464,363 (+)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Oas3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1359319
Created: 2005-07-29
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.