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Gene: Acat2 (acetyl-CoA acetyltransferase 2) Rattus norvegicus
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Symbol: Acat2
Name: acetyl-CoA acetyltransferase 2
Description: Exhibits acetyl-CoA C-acetyltransferase activity. Involved in several processes, including animal organ development; cellular response to fatty acid; and ketone body catabolic process. Localizes to the cytosol. Human ortholog(s) of this gene implicated in coronary artery disease. Orthologous to human ACAT2 (acetyl-CoA acetyltransferase 2); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; INTERACTS WITH 1-(3-(trifluoromethyl)phenyl)piperazine; 1-benzylpiperazine; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Ab2-076; Acat3; acetyl-CoA acetyltransferase, cytosolic; acetyl-Coenzyme A acetyltransferase 2; acetyl-Coenzyme A acetyltransferase 3; cytosolic acetoacetyl-CoA thiolase; MGC95138; similar to acetyl CoA transferase-like
Orthologs:
Homo sapiens (human) : ACAT2 (acetyl-CoA acetyltransferase 2)  HGNC  Alliance
Mus musculus (house mouse) : Acat2 (acetyl-Coenzyme A acetyltransferase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acat2 (acetyl-CoA acetyltransferase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ACAT2 (acetyl-CoA acetyltransferase 2)
Canis lupus familiaris (dog) : ACAT2 (acetyl-CoA acetyltransferase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acat2 (acetyl-CoA acetyltransferase 2)
Sus scrofa (pig) : ACAT2 (acetyl-CoA acetyltransferase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0147,972,399 - 47,992,654 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0151,757,961 - 51,776,935 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4141,922,020 - 41,940,074 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1141,924,964 - 41,943,018 (+)NCBI
Celera143,380,977 - 43,399,019 (+)NCBICelera
Cytogenetic Map1q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Acat2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1359366
Created: 2005-07-29
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.