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Gene: Akr1c12 (aldo-keto reductase family 1, member C12) Rattus norvegicus
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Symbol: Akr1c12
Name: aldo-keto reductase family 1, member C12
Description: Predicted to have bile acid binding activity; ketosteroid monooxygenase activity; and oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Predicted to be involved in glycoside metabolic process; progesterone metabolic process; and prostaglandin metabolic process. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in 46,XY sex reversal 8; B-lymphoblastic leukemia/lymphoma; T-cell acute lymphoblastic leukemia; and leukemia. Orthologous to several human genes including AKR1C1 (aldo-keto reductase family 1 member C1); AKR1C2 (aldo-keto reductase family 1 member C2); and AKR1C3 (aldo-keto reductase family 1 member C3).
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 17beta-hydroxysteroid dehydrogenase; Akr1c13; aldo-keto reductase family 1, member C13; BER1; liver regeneration-related protein LRRG07; LOC364773; LOCT364773; similar to liver regeneration-related protein LRRG07; TBER1; TBER1-S; x56
Orthologs:
No known orthologs. homologs ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01769,695,532 - 69,711,654 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1769,695,550 - 69,711,689 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01771,405,295 - 71,421,030 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41777,203,587 - 77,219,705 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11777,214,420 - 77,230,538 (-)NCBI
Celera1765,562,448 - 65,578,567 (-)NCBICelera
Cytogenetic Map17q12.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Akr1c12
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1359406
Created: 2005-07-29
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.