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Gene: Ctnna1 (catenin alpha 1) Rattus norvegicus
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Symbol: Ctnna1
Name: catenin alpha 1
Description: Predicted to have several functions, including beta-catenin binding activity; cytoskeletal protein binding activity; and gamma-catenin binding activity. Involved in several processes, including axon regeneration; gap junction assembly; and gonad development. Localizes to acrosomal vesicle; adherens junction; and plasma membrane. Biomarker of esophageal cancer and lung carcinoma. Human ortholog(s) of this gene implicated in patterned macular dystrophy 2. Orthologous to human CTNNA1 (catenin alpha 1); PARTICIPATES IN E-cadherin signaling pathway; N-cadherin signaling pathway; vascular endothelial growth factor signaling pathway; INTERACTS WITH 1,3-dinitrobenzene; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: catenin (cadherin associated protein), alpha 1; catenin (cadherin-associated protein), alpha 1; catenin (cadherin-associated protein), alpha 1, 102kDa; catenin alpha-1; catenin, alpha 1; Catna1; MGC93767
Orthologs:
Homo sapiens (human) : CTNNA1 (catenin alpha 1)  HGNC  Alliance
Mus musculus (house mouse) : Ctnna1 (catenin (cadherin associated protein), alpha 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ctnna1 (catenin alpha 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CTNNA1 (catenin alpha 1)
Canis lupus familiaris (dog) : CTNNA1 (catenin alpha 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ctnna1 (catenin alpha 1)
Sus scrofa (pig) : CTNNA1 (catenin alpha 1)
Chlorocebus sabaeus (African green monkey) : CTNNA1 (catenin alpha 1)
Heterocephalus glaber (naked mole-rat) : Ctnna1 (catenin alpha 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01827,923,229 - 28,055,972 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1827,923,572 - 28,055,960 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01827,633,009 - 27,766,069 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41827,629,915 - 27,769,360 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11827,656,560 - 27,796,004 (+)NCBI
Celera1826,463,736 - 26,596,152 (+)NCBICelera
Cytogenetic Map18p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Ctnna1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1359485
Created: 2005-07-29
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.