Gene: Itch (itchy E3 ubiquitin protein ligase) Rattus norvegicus
Analyze
Symbol: Itch
Name: itchy E3 ubiquitin protein ligase
Description: Predicted to have several functions, including CXCR chemokine receptor binding activity, arrestin family protein binding activity, and ligase activity; predicted to be involved in several processes, including cellular protein metabolic process, negative regulation of NF-kappaB transcription factor activity, and regulation of protein metabolic process; predicted to colocalize with the early endosome; orthologous to human ITCH (itchy E3 ubiquitin protein ligase); PARTICIPATES IN Notch signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; tumor necrosis factor mediated signaling pathway; INTERACTS WITH atrazine; bisphenol A; gentamycin.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: E3 ubiquitin-protein ligase Itchy homolog; itch E3 ubiquitin ligase; itchy E3 ubiquitin protein ligase homolog; itchy E3 ubiquitin protein ligase homolog (mouse); itchy homolog E3 ubiquitin protein ligase; itchy homolog E3 ubiquitin protein ligase (mouse); itchy, E3 ubiquitin protein ligase
Orthologs:
Homo sapiens (human) : ITCH (itchy E3 ubiquitin protein ligase)  HGNC  Alliance
Mus musculus (house mouse) : Itch (itchy, E3 ubiquitin protein ligase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itch (itchy E3 ubiquitin protein ligase)
Pan paniscus (bonobo/pygmy chimpanzee) : ITCH (itchy E3 ubiquitin protein ligase)
Canis lupus familiaris (dog) : ITCH (itchy E3 ubiquitin protein ligase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itch (itchy E3 ubiquitin protein ligase)
Sus scrofa (pig) : ITCH (itchy E3 ubiquitin protein ligase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03150,660,665 - 150,752,016 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03157,055,848 - 157,117,955 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43145,644,315 - 145,707,190 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13145,549,936 - 145,612,812 (+)NCBI
Celera3142,396,380 - 142,459,141 (+)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Itch
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1359556
Created: 2005-07-29
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.