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Gene: Esrrb (estrogen-related receptor beta) Rattus norvegicus
Symbol: Esrrb
Name: estrogen-related receptor beta
CRRD ID: 1359557
Description: Predicted to have several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II complex binding activity. Involved in positive regulation of glycogen biosynthetic process and positive regulation of glycolytic process. Predicted to colocalize with integrator complex. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 35. Orthologous to human ESRRB (estrogen related receptor beta); INTERACTS WITH 17beta-estradiol; 2,3,7,8-Tetrachlorodibenzofuran; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ERR-beta; Err2; Errb; estrogen receptor-like 2; estrogen-related receptor, beta; nuclear receptor subfamily 3 group B member 2; steroid hormone receptor ERR2
Homo sapiens (human) : ESRRB (estrogen related receptor beta)  HGNC  Alliance
Mus musculus (house mouse) : Esrrb (estrogen related receptor, beta)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Esrrb (estrogen related receptor beta)
Pan paniscus (bonobo/pygmy chimpanzee) : ESRRB (estrogen related receptor beta)
Canis lupus familiaris (dog) : ESRRB (estrogen related receptor beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Esrrb (estrogen related receptor beta)
Sus scrofa (pig) : ESRRB (estrogen related receptor beta)
Chlorocebus sabaeus (African green monkey) : ESRRB (estrogen related receptor beta)
Heterocephalus glaber (naked mole-rat) : Esrrb (estrogen related receptor beta)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.06110,360,940 - 110,458,406 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6110,410,141 - 110,455,906 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06119,600,549 - 119,756,691 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46110,589,116 - 110,635,158 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X146,790,537 - 146,792,860 (+)NCBI
Celera6103,940,309 - 103,986,414 (+)NCBICelera
Cytogenetic Map6q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Esrrb
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1359557
Created: 2005-07-29
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.