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Gene: Tnfsf12 (TNF superfamily member 12) Rattus norvegicus
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Symbol: Tnfsf12
Name: TNF superfamily member 12
Description: Predicted to have tumor necrosis factor receptor binding activity. Predicted to be involved in extrinsic apoptotic signaling pathway; positive regulation of extrinsic apoptotic signaling pathway; and positive regulation of protein catabolic process. Predicted to localize to the extracellular region and perinuclear region of cytoplasm. Orthologous to several human genes including TNFSF12 (TNF superfamily member 12); PARTICIPATES IN cytokine mediated signaling pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: TNF-related weak inducer of apoptosis; Tnlg4a; tumor necrosis factor ligand 4a; tumor necrosis factor ligand superfamily member 12; tumor necrosis factor superfamily member 12; TWEAK
Orthologs:
Homo sapiens (human) : TNFSF12 (TNF superfamily member 12)  HGNC  Alliance
Mus musculus (house mouse) : Tnfsf12 (tumor necrosis factor (ligand) superfamily, member 12)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : TNFSF12 (TNF superfamily member 12)
Canis lupus familiaris (dog) : TNFSF12 (tumor necrosis factor (ligand) superfamily, member 12)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnfsf12 (TNF superfamily member 12)
Sus scrofa (pig) : TNFSF12 (TNF superfamily member 12)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01056,290,780 - 56,300,137 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01056,036,418 - 56,045,765 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41056,503,756 - 56,513,053 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11056,517,378 - 56,526,676 (-)NCBI
Celera1053,558,386 - 53,567,669 (-)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Tnfsf12
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1359620
Created: 2005-07-29
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.