Gene: Kars (lysyl-tRNA synthetase) Rattus norvegicus
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Symbol: Kars
Name: lysyl-tRNA synthetase
Description: Exhibits anion binding activity, lysine-tRNA ligase activity, and tRNA binding activity; involved in several processes, including basophil activation involved in immune response, cellular protein metabolic process, and diadenosine tetraphosphate biosynthetic process; localizes to the aminoacyl-tRNA synthetase multienzyme complex, cytosol, and nucleus; biomarker of sciatic neuropathy; orthologous to human KARS (lysyl-tRNA synthetase); PARTICIPATES IN aminoacyl-tRNA biosynthetic pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; acrylamide; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: lysine--tRNA ligase; LysRS; MGC94484
Orthologs:
Homo sapiens (human) : KARS (lysyl-tRNA synthetase)  HGNC  Alliance
Mus musculus (house mouse) : Kars (lysyl-tRNA synthetase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kars (lysyl-tRNA synthetase)
Pan paniscus (bonobo/pygmy chimpanzee) : KARS (lysyl-tRNA synthetase)
Canis lupus familiaris (dog) : KARS (lysyl-tRNA synthetase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kars (lysyl-tRNA synthetase)
Sus scrofa (pig) : KARS (lysyl-tRNA synthetase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01944,212,205 - 44,231,209 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01955,018,815 - 55,037,820 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41941,927,508 - 41,946,461 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11941,932,389 - 41,951,342 (-)NCBI
Celera1939,318,292 - 39,337,236 (-)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Kars
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1359653
Created: 2005-07-29
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.